PSII function recovered entirely one day after heat stress at 43uC, implying that sweet sorghum has certain capacity to protect itself against heat stress through physiological regulation. When temperature reached 48uC, OEC and PSII reaction center were damaged, as increase in Vk and decrease in RC/ABS were greatly significant. As a result, photosynthetic electron donation to PSI was sharply lowered, and PSI re-reduction became impossible. One day after the stress, the leaves could not recover and tended to die. The inreversible damage on PSII at this temperature should result from heat-induced protein denaturation and lipid oxidation. In conclusion, PSI photochemical capacity was not affected by heat stress in sweet sorghum. Electron transport of PSII acceptor side was initially inhibited by heat stress, and the fragment from QA to 
PQH2 is the most heat sensitive in the electron transport chain between PSII and PSI. The decrease in electron transport between PSII and PSI may play a self-protection role in reducing the possibility of PSI photoinhibition. In this meta-analysis, we dealt with highly significant heterogeneity between the 18 studies. This heterogeneity could potentially affect the meta-analysis results. We only included studies that used immunohistochemistry to reduce heterogeneity as much as possible. However, the source and dilution of primary antibodies, evaluation standards, study location and adjuvant therapy conditions were quite different across studies, creating significant heterogeneity. Accordingly, we used random effects models to analyze the data, but the models did not identify the source of heterogeneity. To clarify the source of heterogeneity in this study, we performed stratified analysis according to study location, source of primary antibodies, evaluation standards and adjuvant therapy condition. In this study, we showed that b-catenin overexpression in the nucleus was significantly correlated with progress Pyrimidine dimers or pyrimidine-pyrimidone photoproducts PPs from the DNA in a reaction called photoreactivation disease and a worse prognosis of CRC. Large, well-designed prospective studies are required to investigate the precise prognostic significance of bcatenin overexpression in the nucleus. Vascular aging is characterized by increased oxidative stress and proinflammatory phenotypic alterations. Metabolic stress, such as chronic hyperglycemia in diabetes, is known to increase the production of reacting oxygen species and promote inflammatory gene expression, accelerating vascular aging. Vascular smooth muscle cells are sensitive to inflammatory lesions, and notable responses thereof such as proliferation and migration are accompanied by enhanced expression of proinflammatory cytokines, especially TNF-a. Agents endowed with inhibitory effects on VSMC responses such as those underlying neointima formation may be suitable for intervention in vascular disease. Silent information regulator of gene transcription 1 is a prominent member of a family of NAD-dependent enzymes and affects a variety of cellular functions ranging from gene silencing.