In vivo biotinylation of the Axitinib virion was thereby achieved without adding extra processing steps. In the examples above, the pIII and pVII fusions are found on separate genetic elements ; hence only low valence pIII is achieved. Using the genome display vector f37, we also show that pIII and pVII fusions are equally well tolerated when encoded in the same vector rendering multivalent bispecific display. This genomic system also offers the potential advantage of simplifying and speeding up the turn over time during propagation as no helper phage super infection step in conjunction with controlled bacterial growth and processing steps are needed. Finally, we show that one virion population can be retrieved after mixing with a different virion population, using the pVII fusion tag. Importantly, the separation of the virion particles takes place in solution before any selective propagation step. Differential tagging of e.g. two separate pIII libraries would allow library against library selection and physically distinguish between two populations of virions independently of their POIs displayed. Although not explored here, it is highly conceivable that type 7 offers an attractive alternative to current type 3 display for construction of and affinity selection from large peptide libraries. Since pIII is of particular importance for early events in E. coli entry, a complete lack of infectivity interference is expected when pIII is wt. Indeed, in a direct comparison between signal sequence-dependent genomic pIII and pVII display, Kwasnikowski et al. reported superior antigen reactivity with pVII display. It may well be that signal sequence independent peptide libraries offer an additional advantage due to lack of heterogeneous leader peptidase processing. An additional advantage to pVII display, leaving pIII unaltered, is that virion rescue following a library selection step may be performed without breaking the virion-target bond, as elution may be done by infection directly on the solid phase. Especially for retrieving high affinity binders, when the strong virion-target interaction may be resistant to a variety of elution strategies, this simplifies rescue and may well increase the successful isolation of such binders. The mechanism of Danshen is still not clear but its inhibitive effect on platelet adhesion and aggregation might be one of the important bases for its cardiovascular effects. Both crude extract of Danshen and purified compounds such as SB were reported to exhibit inhibitory effects on platelet aggregation and adhesion. Our previous study also showed that salvianolic acids isolated from Salvia miltiorrhiza could inhibit ADP induced platelet aggregation of rat platelets both in vitro and ex vivo.